2021September 3, year，European Chemicals Agency(ECHA)Public consultation was conducted on the four substances proposed for inclusion in the list of Substances of Very High Concern (SVHC).，Information on these substances is shown in the table below。Public consultation is open until 18 October 2021。
| # | The name of the substance | EC number | CAS number | Proposed country | Rationale for the proposal |
| 1 | (±)-1,7,7-Trimethyl-3-[(4-Methyl phenyl)methylene]Second Ring[2.2.1]Hept-2-one，This includes individual isomers and/or combinations thereof(4-MBC) | — | — | Denmark | Endocrine disrupting (Art. 57f.) – to human health) |
| 2 | 2,2′-Methylene bis(4-Methyl-6-tert-butylbenzene(DBMC) | 204-327-1 | 119-47-1 | Denmark | Reproductive toxicity (Section 57c) |
| 3 | S-(Three rings[5.2.1.0’2,6]Decan-3-en-8(or 9)-base) O-(Isopropyl or isobutyl or 2-ethylhexyl) O-(Isopropyl or isobutyl or 2-ethylhexyl)Phosphorothioate | 401-850-9 | 255881-94-8 | Belgium | Persistence、Bioaccumulation and toxicity(PBT)(Section 57d) |
| 4 | Vinyl - three(2-Methoxy Ethoxy group)Silanes |
213-934-0 | 1067-53-4 | Austria | Reproductive toxicity (Section 57c) |